ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " Disulfide bond "

ターゲット

16

阻害剤

1

天然化合物

20

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T2568L Felypressin acetate 2-(L-Phenylalanine)-8-L-lysinevasopressin,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2 Vasopressin Receptor
Felypressin acetate (PLV-2) is an agonist of vasopressin 1 and acts on all arginine vasopressin receptors 1AS. Felypressin acetate can be used in dental procedures.
T19925 EcDsbB-IN-9 Others
EcDsbB-IN-9 is a specific EcDsbB inhibitor, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria.
T8587 EcDsbB-IN-12 4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one Others
EcDsbB-IN-12 (4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one) targets disulfide bond forming enzyme,and is a novel potent specific inhibitor of EcDsbB.
T15076 DBCO-S-S-PEG3-biotin Others , PROTAC Linker
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents s...
TP1604L Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base) Others
Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active...
T17731L CL2A-SN-38 DCA 1279680-68-0(free base) Others
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito...
T38312 L-Cysteine-glutathione disulfide
L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to p...
T35251 YK-5-252 YK 5 252,YK5-252,YK-5252
YK-5-252 is a dual action combretastatin A-4 (CA-4) prodrug which releases CA-4 through a disulfide bond cleavage mechanism and contains a near-infrared (NIR) fluorophore.
T17505 Azido-PEG3-SS-NHS Others
Azido-PEG3-SS-NHS is a three-unit polyethylene glycol (PEG) linker functionalized with an azide group, a cleavable disulfide bond, and an N-hydroxysuccinimide ester. It is primarily employed in the synthesis of antibody-...
T11059 DM4-SMe Others
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds ...
T17732 CL2A Others
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuz...
TP1604 Thioredoxin reductase peptide
Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi...
T76480 Amylin (1-37) (human)
Amylin (1-37) (human) (hIAPP (1-37)), a peptide hormone found in pancreatic beta-cell secretory granules, features an amidated C-terminus and a disulfide bond between cysteine residues 2 and 7 [1].
T80992 Thrombospondin (TSP-1)-derived CD36 binding motif
Thrombospondin-1 (TSP-1)-derived CD36 binding motif is a bioactive peptide cyclized by a disulfide bond, critical for TSP-1-CD36 interaction. Involved in cancer metastasis, tumor adhesion, and angiogenesis, this matrix-b...
T80255 CHRG01
CHRG01, a biologically active peptide, originates from the C-terminal amino acids 54 to 67 of human β-defensin 3 (hBD-3), with a modified structure wherein all cysteine (Cys) residues are replaced by serine (Ser) to elim...
T17731 CL2A-SN-38 Others
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific ant...
カタログ番号 製品名 別名 ターゲット
T1085L Glutathione oxidized Bi(glutathion-S-yl),Oxidized glutathione,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
Glutathione oxidized (L(-)-Glutathione) is a GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPH-01340 Filaggrin Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. Filaggrin Protein, Human, Recombinant (His) is expr...
TMPY-02887 IFI30 Protein, Human, Recombinant (His) Human HEK293 Cells
IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat...
TMPJ-00902 Kell Protein, Human, Recombinant (His) Human HEK293 Cells
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in sk...
TMPY-02890 ERP27 Protein, Human, Recombinant (mFc) Human HEK293 Cells
ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide...
TMPJ-00301 Coagulation Factor X Protein, Human, Recombinant (hFc) Human HEK293 Cells
F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a...
TMPJ-01020 GFER Protein, Human, Recombinant (His) Human E. coli
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isofo...
TMPJ-00824 Ig lambda constant 2 Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recogniti...
TMPY-04626 Enterokinase/EK Protein, Bovine, Recombinant Bovine P. pastoris (Yeast)
Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the ...
TMPY-02768 Selenoprotein M Protein, Human, Recombinant (His) Human E. coli
Selenoprotein M is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine M is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenopr...
TMPJ-00056 AG-2 Protein, Human, Recombinant (His) Human HEK293 Cells
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcin...
TMPH-02249 TRIM72 Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon mem...
TMPJ-01116 HABP2 Protein, Human, Recombinant (His) Human HEK293 Cells
Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50...
TMPJ-01290 Neurturin Protein, Human, Recombinant Human E. coli
Neurturin is a member of the GDNF family of ligands, which include glial cell-derived neurotrophic factor (GDNF), Neurturin, Persephin, and Artemin. Neurturin is expressed in both neuronal and nonneuronal tissues. Simila...
TMPY-02839 Adrenomedullin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the ca...
TMPY-00821 HGFA Protein (pro form), Human, Recombinant (His) Human HEK293 Cells
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the act...
TMPY-01190 INHBB Protein, Human, Recombinant (His) Human HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...
TMPY-01846 Activin A Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...
TMPY-02211 USP5 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Ubiquitin carboxyl-terminal hydrolase 5, also known as Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thiolesterase 5, Ubiquitin-specific-processing protease 5, ISOT and USP5, is a member of the peptidase C19 famil...
TMPH-03741 BoNT/F Protein, Clostridium botulinum, Recombinant (His) Clostridium botulinum E. coli
Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequen...
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
TMPY-01104
Species: Human
Expression System: HEK293 Cells
Filaggrin Protein, Human, Recombinant (His)
TMPH-01340
Species: Human
Expression System: P. pastoris (Yeast)
IFI30 Protein, Human, Recombinant (His)
TMPY-02887
Species: Human
Expression System: HEK293 Cells
Kell Protein, Human, Recombinant (His)
TMPJ-00902
Species: Human
Expression System: HEK293 Cells
ERP27 Protein, Human, Recombinant (mFc)
TMPY-02890
Species: Human
Expression System: HEK293 Cells
Coagulation Factor X Protein, Human, Recombinant (hFc)
TMPJ-00301
Species: Human
Expression System: HEK293 Cells
GFER Protein, Human, Recombinant (His)
TMPJ-01020
Species: Human
Expression System: E. coli
Ig lambda constant 2 Protein, Human, Recombinant (His)
TMPJ-00824
Species: Human
Expression System: HEK293 Cells
Enterokinase/EK Protein, Bovine, Recombinant
TMPY-04626
Species: Bovine
Expression System: P. pastoris (Yeast)
Selenoprotein M Protein, Human, Recombinant (His)
TMPY-02768
Species: Human
Expression System: E. coli
AG-2 Protein, Human, Recombinant (His)
TMPJ-00056
Species: Human
Expression System: HEK293 Cells
TRIM72 Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-02249
Species: Human
Expression System: E. coli
HABP2 Protein, Human, Recombinant (His)
TMPJ-01116
Species: Human
Expression System: HEK293 Cells
Neurturin Protein, Human, Recombinant
TMPJ-01290
Species: Human
Expression System: E. coli
Adrenomedullin Protein, Human, Recombinant (hFc)
TMPY-02839
Species: Human
Expression System: HEK293 Cells
HGFA Protein (pro form), Human, Recombinant (His)
TMPY-00821
Species: Human
Expression System: HEK293 Cells
INHBB Protein, Human, Recombinant (His)
TMPY-01190
Species: Human
Expression System: HEK293 Cells
Activin A Protein, Mouse, Recombinant (His)
TMPY-01846
Species: Mouse
Expression System: HEK293 Cells
USP5 Protein, Human, Recombinant (His)
TMPY-02211
Species: Human
Expression System: Baculovirus Insect Cells
BoNT/F Protein, Clostridium botulinum, Recombinant (His)
TMPH-03741
Species: Clostridium botulinum
Expression System: E. coli
カタログ番号 製品名
L9410 Covalent Inhibitor Library

1920 compounds
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);